Cheng B, Deng H, Zhao Y, Zhu F, Liang H, Li C, Zhong R, Li J, Xiong S, Chen Z, Liang W, He J Cancer Management and Research 2021 , 13:977-985 Published Date: 3 February 2021 1c and d). Food. 4. The exclusion criteria included patients with previously treated OCCC, Overexpression of RALY promotes migration and predicts poor prognosis in hepatocellular carcinoma . Therefore, the development of innovative therapeutic strategies and precision medicine for the treatment of OCCC are important. 5. 4. OCCC has a more unfavorable clinical outcome due to a poor response to platinum-based chemotherapy, compared with serous carcinoma. OCCC has a lot of offer, but you must want those opportunities in order to experience them to the fullest 1 person found this useful 0 people did not find this useful report this rating. (D) Patients with PD-L1 high (blue dotted line) showed significantly worse PFS compared with those with low expression (yellow solid line). OC&C Strategy Consultants help top management of major multinational corporations and leading national companies as well as private equity firms, governmental and other public institutions develop winning strategies. Given the extensive expression of TF in OCCC tumors, it is unlikely IHC expression will be useful in risk stratification for VTE in this population. Muztagh Ata to determine its seasonal variation, transport, and potential contribution source areas. Systematic analysis of molecular mechanisms for HCC metastasis via text mining approach. Clubs. The daily EBC concentrations ranged from 33.6 to 330.2 ng m–3 with an average of 133.1 ± 55.0 ng m–3 during the period. (C) AZD8055 and everolimus IC 50 determined for 14 OCCC cell lines (ES2, KOC7C, SMOV2, JHOC5, RMG1, OVMANA, HAC2, OV207, OVTOKO, TOV21G, OVAS, OVCA429, TUOC1 and RMG2) by MTT assay. All 29 clinical trial groups of GCIG participated in program development and deliberations. We bring fresh insight, clarity and deep industry expertise to the table, dig into the numbers, and come up with pragmatic, creative solutions that have lasting impact. COVID-19 is a virus identified as the cause of an outbreak of respiratory illness that has spread globally into a pandemic. 12/04/2019. Facilities. (A, B) PFS and OS curves in patients with OCCC. Internet. The OCC control problem is an optimal control problem that is concerned with minimizing control effort subject to multiple performance constraints on output covariance matrices. Nano Energy 26, 620-630, 2016. Additionally, in the curve of OCCC the characteristic adsorption peak at 1305 and 1648 cm − 1 belonged to the C N and C O stretching vibration absorption peak in amido group were observed, suggesting that in the preparation of OCCC there was an condensation reaction between the anhydride of hexahydrophthalic anhydride and the amino in chitosan. 5. Epub 2019 May 22. The p-values were calculated by log-rank test. Peipei a,Wang,a Yangyang Zhu, b Xiaoyan Wang,a Xinyu Zhang,a Wenyuan Zhu,a Chunli c Yao, and Junlong Songa,* Water-soluble amphoteric polyacrylamide (AmPAM) has been widely used in papermaking as one of the agents for the improvement of dry strength. However, little information about the expression pattern of SNHG6 in ovarian clear cell carcinoma (OCCC) is available, and the contributions of this long non-co … Long non-coding RNA SNHG6 promotes cell proliferation and migration through sponging miR-4465 in ovarian clear cell carcinoma J Cell Mol Med. Conclusions TFMV activity and plasma TF level were not predictive of VTE in this patient population. As shown in Fig. (B,C) The OCCC cell lines TOV21G and RMG‐1 were transfected with small interfering RNAs (siRNAs), and the ES‐2 and OVCA420 cell lines were transfected with SNHG6 overexpression plasmids. 5. 2018; 10 :5559-72 An international, peer-reviewed, open access journal focusing on cancer research and the optimal use of preventative and integrated treatment interventions to achieve improved outcomes, enhanced survival and quality of life for the cancer patient. Dysregulation of small nucleolar RNA host gene 6 (SNHG6) exerts critical oncogenic effects and facilitates tumourigenesis in human cancers. Patients A total of 138 patients diagnosed with OCCC were selected from the archival collections (between 1999 and 2014) of the Department of Pathology at Fudan University Shanghai Cancer Center. Location. Hong Gang ZHU Ran Yuan WANG Bin Meng CHEN Current Assignee (The listed assignees may be inaccurate. Clinicopathological features of ovarian clear cell carcinoma associated with ovarian endometriosis Ovarian clear cell carcinoma (OCCC) is the second most common ovarian cancer after serous carcinoma in Japan. The mutation spectrum revealed C: G > T: A transitions (69.41%), as the most abundant alteration, and other transversions, including C: G > G: C (6.91%), T: A > C: G (7.83%), C: G > A: T (1.02%), T: A > G: C (2.25%) and T: A > A: T (3.37%) (Fig. 01.01.2020 | Original Paper | Ausgabe 1/2020 Prehabilitation for patient positioning: pelvic exercises assist in minimizing inter-fraction sacral slope variability during radiation therapy. Semantic Scholar profile for Zhongyi Zhu, with 4 highly influential citations and 14 scientific research papers. Yudan Wei, Jianmin Zhu. Oncotarget. OCCC encourages you to learn more about COVID-19, health and safety precautions, and resources at: OCCC Coronavirus Information. Data is derived from n≥2 experiments. MATERIALS AND METHODS 1. Happiness. 5. Opportunities . Social. Applied Surface Science 279, 416-423, 2013. Refined Docking as a valuable Tool for Lead Optimization: Application to Histamine H3 Receptor Antagonists . Abstract: Objective To investigate the expressions of CD44,CD47,and c-met in ovarian clear cell carcinoma (OCCC) tissue and their correlations with clinical variables and prognosis.Methods Immunohistochemical method was used to investigate the expressions of CD44,CD47,and c-met in tissues from 86 OCCC patients and the relationships of their expressions with the clinicopathological … 2019 Aug;23(8):5025-5036. doi: 10.1111/jcmm.14359. Measurements of equivalent black carbon (EBC) were conducted for 8 months from November 2009 to September 2010 at Mt. OCCC patients had greater expression of TF in their tumors than patients with HGSOC, p<0.0001. In this paper, the output covariance constraint (OCC) control problem is cast as a convex optimization with linear matrix inequality (LMI) constraints. The efficiency of knockdown or overexpression was verified by qRT‐PCR. Multifunctional materials have rapidly attracted increasing attention owing to their novel, unpredictable, and unique properties, and potential applications in sensors, switches and smart materials. In OCCC patients with low ARIDA1 expression, the decreased CD8 T cell fraction and CD274 (PD-L1) expression are related to type II immunological ignorance. OCCC has differing prevalence rates depending on race and ethnicity, and has greater prevalence in Asia than in western countries [9, 10]. Therefore, immunotherapies are attracting attention, including the GPC3 peptide vaccine, which improves overall survival. Nicolas Levoin*1, Thierry Calmels1, Olivia Poupardin-Olivier1, Olivier Labeeuw1, Denis Danvy1, Philippe Robert1, Isabelle Berrebi-Bertrand1, C. Robin Ganellin2, Walter Schunack3, Holger Stark4, Marc Capet1 . prognostic value of PD-L1 expression in OCCC. Reputation. 4. PubMed PubMed Central Article Google Scholar 8. 102: 2016: Electrophoretic deposition of graphene oxide as a corrosion inhibitor for sintered NdFeB. Please help EMBL-EBI keep the data flowing to the scientific community! Ovarian clear cell carcinoma (OCCC) has been treated with surgery and chemotherapy; however, the prognosis remains poor because of chemoresistance. Draft consensus statements were discussed in topic groups as well as in a plenary forum. However, little information about the expression pattern of SNHG6 in ovarian clear cell carcinoma (OCCC) is available, and the contributions of this long non-coding RNA to the tumourigenesis and progression of OCCC are unclear. OCCC is frequently diagnosed in Asian women and is known to exhibit higher chemoresistance than high-grade serous carcinoma, ... Curves showed OS stratified by NLR (A) and PLR (C). Rating categories. Coronavirus Reporting Form for Faculty and Staff. (C) Patients with PD-L1 low (yellow solid line) presented a better survival outcome than those with PD-L1 high (blue dotted line). Hypoxia inducible factor-1α (HIF-1α) is a key regulator of cellular response to hypoxia and plays an important role in tumor growth, and HIF-1α … Zhu Z, Zhang Y, Huang C. et al. Because of the low numbers of CD8 T cells in OCCC, it is unlikely that blocking PD-L1 will lead to a T cell response . Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.) (D,E) Cell Counting Kit‐8 assays were performed to determine the influence of SNHG6 on cell proliferation. Curves showed PFS stratified by NLR (B) and PLR (D). Safety. 5. HGS ovarian cancer cell lines PEA1, PEO14 and OVCAR3 were used as a resistant control, horizontal lines indicate geometric mean of only the OCCC cell lines. Studies have shown that the mTOR signaling pathway is also associated with cancer, arthritis, insulin resistance, osteoporosis, and other diseases. W He, L Zhu, H Chen, H Nan, W Li, H Liu, Y Wang. T Zhang, H Chen, Y Bai, S Xiao, L Zhu, C Hu, Q Xue, S Yang. Here, C is the number of channels and N is the dimension of features from the previous convolutional layer. Zhen C, Zhu C, Chen H, Xiong Y, Tan J, Chen D, et al. Take part in our Impact Survey (15 minutes). The methodology for obtaining consensus was previously established and followed during the Fifth OCCC. Europe PMC is an archive of life sciences journal literature. Cancer Manag Res. In this investigation, AmPAM was used, solely or with the combination of cationic starch (CS), for the strength improvement of paper … Lauren O’Loughlin, Alexander Lukez, Yunsheng Ma, Jennifer Baima, Janaki Moni . Supplemental Material . Ovarian clear cell carcinoma (OCCC) shows low sensitivity to conventional chemotherapy and has a poor prognosis, especially in advanced stages. Mammalian target of rapamycin (mTOR) regulates cell proliferation, autophagy, and apoptosis by participating in multiple signaling pathways in the body. CDC Coronavirus Website 2017;8(8):13909–16. 3, each head of convolutional feature x m ∈ R C ¯ × N is transformed into four feature spaces f, g, k and p by a 1 × 1 convolutions to calculate the attention map, where C ¯ = C / h and h is the number of heads. 5. However, a lack of deeper understanding of performance optimization and structure–property relationships hampe 5.