10.1016/j.cbpa.2014.10.025 [14] Grunwald DJ , Eisen JS . Nat Med 10(5):467–474. Curr Opin Chem Biol. Hope for a people with spinal cord injuries after scientists pinpoint key molecules in zebrafish that help them repair damaged nerves. The 2006 findings were based on 15 years of data tracking more than 12,000 multi-ethnic subjects, and were reported in The New England Journal of Medicine. ... Around 1.5 million years … Stem cell therapy for chronic heart failure: lessons from a 15-year experience. Animal models for heart development and cardiac regeneration. 15 years of zebrafish chemical screening. Headwaters of the zebrafish – emergence of a new model vertebrate. The zebrafish is one of the most important models for both developmental and regenerative biology as it can regrow many injured or amputated tissues such as fins, retinae, optic nerves, spinal cord, brain, hair cells, pancreas, liver, kidney and heart muscle (Kikuchi, 2014). 3.2 The DSC2/R132C substitution affects zebrafish heart function. Zebrafish heart regeneration proceeds through injury-induced proliferation of cardiomyocytes which retain their capacity to divide and proliferate ... Olson EN (2004) A decade of discoveries in cardiac biology. The 2006 findings were based on 15 years of data tracking more than 12,000 multi-ethnic subjects, and were reported in The New England Journal of Medicine. After years of research on the zebrafish, our laboratory has discovered successful behavioral models for zebrafish and goldfish in the areas of learning … A microscopic view of the lymphatic system of a zebrafish won this year's Nikon Small World image competition. 2002;3:717–24. 10.1038/nrg892 [15] Streisinger G , Walker C , Dower N , Knauber D , Singer F . Stunning anti-ageing breakthrough could see humans live to 150 and regenerate organs by 2020 'for the price of a coffee a day' A new technique could see the aging process in humans reduced by 50 years This variant was identified in a Japanese proband with ACM diagnosed at 15 years of age. Zebrafish larvae were incubated in 0.2% Calcein (Sigma), pH 7.5 for 15 min and washed twice in system water. Nat Rev Genet. Rennekamp AJ , Peterson RT . 29 No mutations were found in the RYR2, PKP2, DSG2, DSP, JUP or CASQ2 genes in the patient in our study. C R Biol 334(7):489–496. Researchers at a pair of San Diego-based life science organizations announced today the discovery of a molecule that converts stem cells into healthy heart cells, ending a 15-year … This finding was analogous to the result that randomization of heart looping occurred in nphp2/inversin knockdown experiments in zebrafish. The Dallas Heart Study , a groundbreaking investigation of cardiovascular disease involving thousands of Dallas County residents, was launched in 1999. Larvae were immobilized using 0.003% Tricaine (Sigma) and mounted in 3% methyl cellulose. 2015;24:58–70. Scientists from the University of Oxford found that a gene called lrrc10 is linked to heart regeneration in Mexican tetra fish. But it also hints at a new way to study the waste drainage system of the human brain. The Dallas Heart Study , a groundbreaking investigation of cardiovascular disease involving thousands of Dallas County residents, was launched in 1999.